Oxide Room 208 places 8 people in an old lab controlled by a figure named Doc. The heroes are forcibly connected to his Oxide experiment, a project with an unstable host named Eve. Her sanity failed, causing the experiment to create an organic environment that physically deforms the entire facility. This biomechanical setting, a combination motel and lab, has been the site of terrible acts in the past, and now the main goal for the captives is to find the door to 208 for survival.

Oxide Room 104 — is a soul-chilling single horror game that combines gameplay and action in a quest room set in an old motel. Kidnapped in the power of a ruthless scientist and haunted by a horrible creature, you must try to escape, guided by common sense, as in real life. It all starts when you wake up in the bathroom of the motel, naked, injured and unaware of what happened. You remember the deal fell through, but now the only thing that matters is trying to escape from this horrible place no matter what. From now on, everything you do will lead to one of the extremities. And we warn you that there is only one good way out of all the ways this can end.