Maid Sisters Service is a dating simulator in which the protagonist, a wealthy young man, must rediscover himself and his past. The protagonist's daily life, marred by amnesia following a car accident, revolves around interactions with two sister maids who share his villa. One, Qingmei, is caring, while the other, Shiyue, is passionate. In addition, the protagonist's entourage includes a mysterious secretary, with whom interactions are also part of the daily routine. Gameplay revolves around making decisions throughout the day: in the morning, work assignments are assigned to the maids, while during the day, the player can choose to spend time with women or trade on the stock market.