Arms of God is a roguelike bullet-heaven game. You play as one of ten religious warriors with mechanical arms strapped to their backs. You must clear arenas of hordes of demons to the aggressive soundtrack of DOOM. Each run consists of fifteen waves of varying difficulty. Between battles, you can choose upgrades, many of which provide both advantages and disadvantages—for example, high damage with low health. You can carry up to five weapons at a time in combat: firearms, blades, and holy artifacts. The fusion system allows you to combine two identical weapons into a stronger version or transfer the stats from one weapon to another, freeing up a slot for something new.